[DIYbio] The Drugs That May Never Be Used -- AKA acute radiation syndrome (ARS) drugs

http://cen.acs.org/articles/90/i26/Drugs-Never-Used.html

"
Cleveland BioLabs has been trying to move its lead candidate, CBLB502,
along this development path. The drug is an injectable recombinant
derivative of a bacterial protein flagellin that activates signaling
pathways and suppresses apoptotic cell death in hematopoietic and GI
cells. The firm also is exploring CBLB502 as a radioprotectant in
medical procedures. It has completed animal efficacy and human safety
studies, and it has regulatory-compliant manufacturing.
"

seems like you'd want radiation-damaged cells to apoptose, rather than
continue and possibly mutate into a cancer. CONSPIRACY THEORY: if this
actually got approved, people would think it was great, but it could
in reality just keep them coming back.

This just seems like shrewd marketing by pharma... to keep themselves
in business, the old 'it looks good in short-term, but keeps patients
coming back'



--
Nathan McCorkle
Rochester Institute of Technology
College of Science, Biotechnology/Bioinformatics

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