RE: [DIYbio] At home fabrication of micron scale microfluidics

Would this beat shrinky dink microfluidics? I've managed to make features using shrink sheets printed using a standard toner printer and pdms at around 100-150um and tested with plant protoplasts. With soft lithography, would you use SU-8 or some other material type? How will your software compare to other free CAD programs like draftsight? Will it be photolithography for the master mold production?

Price I would personally pay depends on functionality vs cost. If you can really deliver a simple system (or any system) for production that isn't as finicky as shrinkydinks I'd pay decently for it. It would dave so much time and wasted effort. So much time spent watching templates warp in the toaster oven and whatnot. Also, how will you overcome the hydrophobicity of pdms? I use a corona arch wand but that's not cheap and the microwave method needs a good two stage vacuum pump (also not cheap) so I'm super interested in alternatives.

If the end material is glass or pmma (acrylic) that would be great too. Any thoughts on chip connection and reusability?

Sebastian S. Cocioba
CEO & Founder
New York Botanics, LLC
Plant Biotech R&D

From: Peter Shankles
Sent: ‎2/‎27/‎2015 8:42 AM
To: diybio@googlegroups.com
Subject: [DIYbio] At home fabrication of micron scale microfluidics

Hello all,

I'm new to the DIYbio community and need your perspective on something. 

I'm working on a project that would make microfluidics available to use at home. Because I'm working on this at a national lab, I can't give too many specifics at this time. With that being said our setup would include software for designing devices and creating a master mold for soft lithography. The resolution would be on the order of 100 um, and the fabrication time would be a couple of hours. 

What I want to know is:
  What types of features and designs would be most important to include?
  How much would you be willing to pay for this functionality (software will be open source, but there is hardware as well)?
  What would you be most interested in using microfluidics for?
  Anything else you can think of. I would appreciate any input you have.

Thanks for your time,
Peter

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